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RET, PROTO-ONCOGENE PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Proto-Oncogene Proteins c-ret
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas c-ret
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas c-ret
Synonyms
English
:
Proto Oncogene Protein Ret
Proto Oncogene Protein c ret
Proto Oncogene Proteins c ret
Proto-Oncogene Protein Ret
Proto-Oncogene Protein c-ret
Proto-Oncogene Proteins, ret
Receptor Tyrosine Kinase RET
Ret, Proto-Oncogene Protein
c-ret Protein
c-ret, Proto-Oncogene Protein
c-ret, Proto-Oncogene Proteins
ret Proto Oncogene Proteins
ret Proto-Oncogene Proteins
Tree Number:
D08.811.913.696.620.682.725.400.087
D12.776.395.550.200.188.500
D12.776.543.131.500
D12.776.543.750.630.217
D12.776.624.664.700.194
Definition
English
:
Receptor protein-tyrosine kinases
involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR
ligands
. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS.
Mutations
in ret protein are responsible for
HIRSCHSPRUNG DISEASE
and
MULTIPLE ENDOCRINE NEOPLASIA
TYPE 2.
History Note
English
:
2006(1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50737
Unique Identifier:
D051096
Occurrence in VHL
:
Similar:
DeCS